Publications

Book chapters

Khodaei, S., & Keshavarz-Motamed, Z. (2023). Enhancing Medical Imaging with Computational Modeling for Aortic Valve Disease Intervention Planning. In K. Daimi, A. Alsadoon, & S. Seabra Dos Reis (Eds.), Current and Future Trends in Health and Medical Informatics (pp. 19–46). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-42112-9_2
B. Rahmatikaregar, S. Shirani, Z. Keshavarz-Motamed. (2022). A review of automatic cardiac segmentation using deep learning and deformable models. CRC press Taylor and Francis Group, 29-82. (Book title: Artificial Intelligence in Healthcare and Medicine; Editors: K. Najarian, D. Kahrobaei, E. Dominguez, R. Soroushmehr; ISBN 9781003120902).

Journal Papers

2024

Keshavarz-Motamed, Z. (2024). Ventricular pressure-volume loop and other heart function metrics can elucidate etiology of failure of TAVI and interventions. REC: Interventional Cardiology (English Edition), 13235. https://doi.org/10.24875/RECICE.M23000438 INVITED EDITORIAL
Smith, S., Michalski, P., Carette, J., & Keshavarz-Motamed, Z. (2024). State of the Practice for Lattice Boltzmann Method Software. Archives of Computational Methods in Engineering, 31(1), 313–350. https://doi.org/10.1007/s11831-023-09981-2
Rahmati, B., Shirani, S., & Keshavarz-Motamed, Z. (2024). Redundant co-training: Semi-supervised segmentation of medical images using informative redundancy. Neurocomputing, 579, 127446. https://doi.org/10.1016/j.neucom.2024.127446

2023

Abdelkhalek, M., Bahadormanesh, N., Ganame, J., & Keshavarz-Motamed, Z. (2023). Incremental prognostic value of intensity-weighted regional calcification scoring using contrast CT imaging in TAVR. European Heart Journal – Imaging Methods and Practice, 1(2), qyad027. https://doi.org/10.1093/ehjimp/qyad027
Khodaei, S., Garber, L., Abdelkhalek, M., Maftoon, N., Emadi, A., & Keshavarz‐Motamed, Z. (2023). Reducing Long‐Term Mortality Post Transcatheter Aortic Valve Replacement Requires Systemic Differentiation of Patient‐Specific Coronary Hemodynamics. Journal of the American Heart Association, 12(11), e029310. https://doi.org/10.1161/JAHA.123.029310
Garber, L., Khodaei, S., Maftoon, N., & Keshavarz-Motamed, Z. (2023). Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling. Scientific Reports, 13(1), Article 1. https://doi.org/10.1038/s41598-023-31987-w
Bahadormanesh, N., Tomka, B., Abdelkhalek, M., Khodaei, S., Maftoon, N., & Keshavarz-Motamed, Z. (2023). A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement. Scientific Reports, 13(1), Article 1. https://doi.org/10.1038/s41598-023-33511-6
Khodaei, S., Abdelkhalek, M., Maftoon, N., Emadi, A., & Keshavarz-Motamed, Z. (2023). Early Detection of Risk of Neo-Sinus Blood Stasis Post-Transcatheter Aortic Valve Replacement Using Personalized Hemodynamic Analysis. Structural Heart, 100180. https://doi.org/10.1016/j.shj.2023.100180
Abdelkhalek, M., Daeian, M., Chavarria, J., Sellers, S., Gulsin, G., Leipsic, J., Sheth, T., & Keshavarz-Motamed, Z. (2023). Patterns and Structure of Calcification in Aortic Stenosis. JACC: Cardiovascular Imaging, 16(9), 1224–1226. https://doi.org/10.1016/j.jcmg.2023.02.011
Abdelkhalek, M., Daeian, M., & Keshavarz-Motamed, Z. (2023). Regional assessment of aortic valve calcification using topographic maps in contrast-enhanced CT: In-vivo sex and severity-based differences in calcific presentation. Quantitative Imaging in Medicine and Surgery, 14(1), 19–19. https://doi.org/10.21037/qims-23-778
Bahadormanesh, N., Tomka, B., Kadem, M., Khodaei, S., & Keshavarz-Motamed, Z. (2023). An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis. Medical Image Analysis, 87, 102795. https://doi.org/10.1016/j.media.2023.102795
Rahmati, B., Shirani, S., & Keshavarz-Motamed, Z. (2024). Redundant co-training: Semi-supervised segmentation of medical images using informative redundancy. Neurocomputing, 579, 127446. https://doi.org/10.1016/j.neucom.2024.127446

2022

Z. Keshavarz-Motamed, J. C. del Alamo, D. Bluestein, E. R. Edelman, J. J. Wentzel. (2022). Novel methods to advance diagnostic and treatment value of medical imaging for cardiovascular disease. Frontiers in Bioengineering and Biotechnology (Biomechanics section), 1501. INVITED EDITORIAL
S. Smith, P. Michalski, J. Carette, Z. Keshavarz-Motamed. (2022). State of the practice for Lattice Boltzmann method software. Archives of Computational Methods in Engineering. in press.
R. Sadeghi, B. Tomka, S. Khodaei, J. Garcia, J. Ganame, Z. Keshavarz-Motamed. (2022). Reducing morbidity and mortality in patients with coarctation requires systematic differentiation of impacts of mixed valvular disease on coarctation hemodynamics . Journal of American Heart Association, 11(2): e022664
R. Sadeghi, N. Tomka, S. Khodaei, M. Daeian, K. Gandhi, J. Garcia, Z. Keshavarz-Motamed. (2022). Impact of extra-anatomical bypass on coarctation fluid dynamics using patient-specific lumped parameter and Lattice Boltzmann modeling. Nature Scientific reports. 12 (1): 1-24
M. Kadem, L. Garber, M. Abdelkhalek, B. K. Al-Khazraji, Z. Keshavarz-Motamed. (2022). Hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions. IEEE Reviews in Biomedical Engineering, doi: 10.1109/RBME.2022.3142058. The article was selected by the IEEE RBME as the 2023 Featured Article (published in August 2023).
S. Khodaei, L. Garber, J. Bauer, A. Emadi, Z. Keshavarz-Motamed. (2022). Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics. Nature Scientific reports. in press.
R. Sadeghi, N. Gasner, S. Khodaei, J. Garcia, Z. Keshavarz-Motamed. (2022). Impact of mixed valvular disease on coarctation hemodynamics using patient-specific lumped parameter and Lattice Boltzmann modeling. International Journal of Mechanical Sciences. 217:107038.
L. Garber, S. Khodaei, Z. Keshavarz-Motamed. (2022). The critical role of lumped parameter models in patient-specific cardiovascular simulations. Archives of Computational Methods in Engineering. 1-24.
Y. Wang, A. Biswasa , R. Rodrigueza , Z. Keshavarz-Motamed, A. Emadi. (2022). Hybrid electric vehicle specific engines: state-of-the-art review. Energy reports, 8, 832-851.

2021

S. Khodaei, A. Henstock, R. Sadeghi, S. Sellers, P. Blanke, J. Leipsic, Ali Emadi, Z. Keshavarz-Motamed. (2021). Personalized intervention cardiology with transcatheter aortic valve replacement made possible with a non-invasive monitoring and diagnostic framework. Nature Scientific reports. 11(1): 10888.
M. Baiocchi, S. Barsoum, S. Khodaei, S. E. Valentino, E. C. Dunford, J. M. de la Torre Hernandez, M. J. MacDonald, Z. Keshavarz-Motamed. (2021). Effects of choice of medical imaging modalities on a non-invasive diagnostic and monitoring computational framework for patients with complex valvular, vascular, and ventricular diseases who undergo transcatheter aortic valve replacement. Frontiers in Bioengineering and Biotechnology. 9, 389.
S. Khodaei, R. Sadeghi, P. Blanke, J. Leipsic, A. Emadi, Z. Keshavarz-Motamed. (2021). Towards a non-invasive imaging-based computational diagnostic framework for personalized cardiology of transcatheter aortic valve replacement in interactions with complex valvular, ventricular and vascular disease. International Journal of Mechanical Sciences. 203:10650
M. Asaadi, W. Mawad, A. Djebbari, Z. Keshavarz-Motamed, L. Kadem, N. Dahdah. (2021). On left ventricle stroke work efficiency in children with moderate aortic valve regurgitation or moderate aortic valve stenosis. Pediatric Cardiology, 1-9

2020

Z. Keshavarz-Motamed. (2020). A diagnostic, monitoring, and predictive tool for patients with complex valvular, vascular and ventricular diseases. Nature Scientific Reports. 10:6905
R. Sadeghi, S. Khodaei, J. Ganame, Z. Keshavarz-Motamed. (2020). Towards non-invasive computational-mechanics and imaging-based diagnostic framework for personalized cardiology for coarctation. Nature Scientific Reports. 10:9408. Editor’s choice: fluid dynamics
Z. Keshavarz-Motamed, S. Khodaei, F. Rikhtegar Nezami, J. Mahesh Amrute, S. J. Lee, J. Brown, E. Ben-Assa, S. Sellers, P. Blanke, J. Leipsic, T. Garcia Camarero, J. Ruano Calvo, J. M. de la Torre Hernandez, E. R. Edelman. (2020). Mixed valvular disease following transcatheter aortic valve replacement: quantification and systematic differentiation using clinical measurements and image-based patient-specific in silico modeling. Journal of American Heart Association. 9:e015063

2019

E. Ben-Assa, J. Brown, Z. Keshavarz-Motamed, J. M. de la Torre Hernandez, B. Leiden, M. Olender, F. Kallel, I. F. Palacios, I. Inglessis, P. B. Shah, S. Elmariah, M. B. Leon, E. R. Edelman. (2019). Ventricular stroke work and vascular impedance refine the characterization of patients with aortic stenosis. Science Translational Medicine. 11(509): eaaw0181.

2017

Z. Keshavarz-Motamed, F. Rikhtegar Nezami, R. A. Partida, K. Nakamura, P. V. Staziaki, E. Ben-Assa, B. Ghoshhajra, A. B. Bhatt, E. R. Edelman. (2017). Elimination of trans-coarctation pressure gradients has no impact on left ventricular function or aortic shear stress post intervention in patients with mild coarctation. JACC: Cardiovascular Interventions. 9(18): 1953-1965.
G. Di Labbio, Z. Keshavarz-Motamed, L. Kadem. (2017). Numerical simulation of flows in a circular pipe transversely subjected to a localized impulsive body force with applications to blunt traumatic aortic rupture. Fluid Dynamics Research. 49(3) 035510.

2015

Z. Keshavarz-Motamed, E. R. Edelman, P. K. Motamed, J. Garcia, N. Dahdah, L. Kadem. (2015). The role of aortic compliance in determination of coarctation severity: lumped parameter modeling, in vitro study and clinical evaluation. Journal of Biomechanics. 48(16): 4229-4237.
Z. Keshavarz-Motamed, P. K. Motamed, N. Maftoon. (2015). Non-invasive determination of aortic valve trans-catheter pressure gradient: an analytical model. Medical Engineering & Physics. 37(3): 321-327.
E. Benevento, A. Dejebbari, Z. Keshavarz-Motamed, R. Cecere, L. Kadem. (2015). Hemodynamic changes following aortic valve bypass: A mathematical approach. PLoS One. 10(4): e0123000.

2014

Z. Keshavarz-Motamed, J. Garcia, E. Gaillard, R. Capoulade, F. LeVen, G. Cloutier, L. Kadem, P. Pibarot. (2014). Non-invasive determination of left ventricular workload in patients with aortic stenosis using magnetic resonance imaging and Doppler echocardiography. PLoS One. 9(1): e86793.
Z. Keshavarz-Motamed, Y. Saijo, Y. Majdouline, J. Ohayon, G. Cloutier. (2014). Coronary artery atherectomy stabilizes plaque shear strains: an endovascular elastography imaging study. Atherosclerosis. 235(1): 140-149.
Z. Keshavarz-Motamed, J. Garcia, E. Gaillard, N. Maftoon, G. Di Labbio, G. Cloutier, L. Kadem. (2014). Effect of coarctation of the aorta and bicuspid aortic valve on flow dynamics and turbulence in the aorta using particle image velocimetry. Experiments in Fluids. 55: 1696.
Y. Majdouline, J. Ohayon, Z. Keshavarz-Motamed, M. H. Roy Cardinal, D. Garcia, L. Allard, S. Lerouge, F. Arsenault, G. Soulez, G. Cloutier. (2014). Endovascular shear strain elastography for detection and characterization the severity of atherosclerotic plaques: in vitro validation and in vivo evaluation. Ultrasound in Medicine & Biology. 40(5): 890-903.

2013

Z. Keshavarz-Motamed, J. Garcia, L. Kadem. (2013). Fluid dynamics of coarctation of the aorta and effect of bicuspid aortic valve. PLoS One. 8(8): e72394.

2012

Z. Keshavarz-Motamed, J. Garcia, N. Maftoon, E. Bedard, P. Chetaille, L. Kadem. (2012). A new approach for the evaluation of the severity of coarctation of the aorta using Doppler velocity index and effective orifice area: in vitro study and clinical implications. Journal of Biomechanics. 45(7): 1239-1245.

2011

Z. Keshavarz-Motamed, J. Garcia, P. Pibarot, L. Kadem. (2011). Modeling the impact of concomitant aortic stenosis and coarctation of the aorta on left ventricular workload. Journal of Biomechanics. 44(16): 2817-2825.

2010

Z. Keshavarz-Motamed, L. Kadem, A. Dolatabadi. (2010). Effects of dynamic contact angle on numerical modeling of electrowetting in parallel plate microchannels. Journal of Microfluidics and Nanofluidics. 8(1): 47-56.
Z. Keshavarz-Motamed, L. Kadem. (2010). Pulsatile flow in a curved tube with coexisting model of aortic stenosis and coarctationof the aorta. Medical Engineering and Physics. 33(3): 315-324.